| dailymed-drugs:1077 | rdf:type | http://www4.wiwiss.fu-berli... | lld:dailymed |
| dailymed-drugs:1077 | rdf:type | dailymed-instance:drugs | lld:dailymed |
| dailymed-drugs:1077 | rdfs:label | Simvastatin (Tablet, Film Coated) | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:dosage | Patients with Homozygous Familial Hypercholesterolemia:<br/>Adolescents (10-17 years of age) with Heterozygous Familial Hypercholesterolemia: National Cholesterol Education Program (NCEP): Highlights of the Report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents. Pediatrics. 89(3):495-501. 1992.<br/>Concomitant Lipid-Lowering Therapy:<br/>Patients taking Cyclosporine or Danazol:<br/>Patients taking Amiodarone or Verapamil:<br/>Patients with Renal Insufficiency: | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:clinicalP... | Pharmacokinetics:<br/>Clinical Studies in Adults:<br/>Modifications of Lipid Profiles:<br/>Clinical Studies in Adolescents: | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:activeIng... | dailymed-ingredient:Simvast... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:genericDr... | http://www4.wiwiss.fu-berli... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:activeMoi... | dailymed-ingredient:Simvast... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Talc | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Hydroxy... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Magnesi... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Lactose... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Pregela... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Titaniu... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Microcr... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Hyprome... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Butylat... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Ascorbi... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Isoprop... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Citric_... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:inactiveI... | dailymed-ingredient:Ferric_... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:116 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:764 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:634 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2839 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:319 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2175 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:561 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:1283 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:1092 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:3977 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:949 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2701 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:3639 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:3730 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:51 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:710 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:307 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:1043 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:1507 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2129 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:3045 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:3166 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:3867 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:270 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:102 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:345 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:535 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:560 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:592 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:604 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:674 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:1154 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:1155 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:1368 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:1471 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2010 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2210 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2652 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2695 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2760 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2794 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:2951 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:3044 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:4095 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:possibleD... | diseasome-diseases:4097 | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:precautio... | General:<br/>Information for Patients:<br/>Drug Interactions:<br/>Other drug interactions:<br/>Carcinogenesis, Mutagenesis, Impairment of Fertility:<br/>Pregnancy:<br/>Nursing Mothers:<br/>Pediatric Use:<br/>Geriatric Use: | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:genericMe... | Simvastatin | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:fullName | Simvastatin (Tablet, Film Coated) | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:adverseRe... | Clinical Adverse Experiences:<br/>In Adults:<br/>Scandinavian Simvastatin Survival Study:<br/>Clinical Adverse Experiences:<br/>Heart Protection Study:<br/>Clinical Adverse Experiences:<br/>Laboratory Tests:<br/>Concomitant Lipid-Lowering Therapy:<br/>Adolescent Patients (ages 10-17 years): | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:warning | Myopathy/Rhabdomyolysis:<br/>Liver Dysfunction: | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:indicatio... | Reductions in Risk of CHD Mortality and Cardiovascular Events:<br/>Patients with Hypercholesterolemia Requiring Modifications of Lipid Profiles:<br/>Adolescent Patients with Heterozygous Familial Hypercholesterolemia (HeFH): The minimum goal of treatment in pediatric and adolescent patients is to achieve a mean LDL-C<130 mg/dL. The optimal age at which to initiate lipid-lowering therapy to decrease the risk of symptomatic adulthood CAD has not been determined.<br/>General Recommendations: | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:represent... | http://www4.wiwiss.fu-berli... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:routeOfAd... | http://www4.wiwiss.fu-berli... | lld:dailymed |
| dailymed-drugs:1077 | dailymed-instance:name | Simvastatin | lld:dailymed |
| http://www4.wiwiss.fu-berli... | dailymed-instance:producesD... | dailymed-drugs:1077 | lld:dailymed |
| diseasome-diseases:116 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:764 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:634 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2839 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:319 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2175 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:561 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:1283 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:1092 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:3977 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:949 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2701 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:3639 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:3730 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:51 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:710 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:307 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:1043 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:1507 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2129 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:3045 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:3166 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:3867 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:270 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:345 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:535 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:560 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:592 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:604 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:674 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:1154 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:1155 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:1368 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:1471 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2010 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2210 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2652 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2695 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2760 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2794 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:2951 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:3044 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:4095 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
| diseasome-diseases:4097 | diseasome-instance:possible... | dailymed-drugs:1077 | lld:diseasome |
