Linked Life Data

CPATH-97186

Source:http://cbio.mskcc.org/cpath#CPATH-97186

Statements in which the resource exists.
SubjectPredicateObjectContext
cpath:CPATH-97186rdf:typehttp://www.biopax.org/relea...lld:biogrid
cpath:CPATH-97186http://www.biopax.org/relea...cpath:CPATH-LOCAL-401825lld:biogrid
cpath:CPATH-97186http://www.biopax.org/relea...cpath:CPATH-LOCAL-401826lld:biogrid
cpath:CPATH-97186http://www.biopax.org/relea...cpath:CPATH-LOCAL-401827lld:biogrid
cpath:CPATH-97186http://www.biopax.org/relea...cpath:CPATH-LOCAL-401828lld:biogrid
cpath:CPATH-97186http://www.biopax.org/relea...cpath:CPATH-LOCAL-401829lld:biogrid
cpath:CPATH-97186http://www.biopax.org/relea...cpath:CPATH-LOCAL-403001lld:biogrid
cpath:CPATH-97186http://www.biopax.org/relea...Chloride intracellular channel protein 3lld:biogrid
cpath:CPATH-97186http://www.biopax.org/relea...CLIC3_HUMANlld:biogrid
cpath:CPATH-97186http://www.biopax.org/relea...cpath:CPATH-LOCAL-401823lld:biogrid
cpath:CPATH-97186http://www.biopax.org/relea...FUNCTION: Can insert into membranes and form chloride ion channels. May participate in cellular growth control. SUBUNIT: Associated with the C-terminal of ERK7. SUBCELLULAR LOCATION: Nucleus. Membrane; Single-pass membrane protein. Cytoplasm. Note=Predominantly nuclear. Some protein was found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity). TISSUE SPECIFICITY: Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas. DOMAIN: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion (By similarity). SIMILARITY: Belongs to the chloride channel CLIC family. SIMILARITY: Contains 1 GST C-terminal domain. SIMILARITY: Contains 1 GST N-terminal domain. SEQUENCE CAUTION: Sequence=AAD16450.1; Type=Frameshift; Positions=28; COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
cpath:CPATH-97186skos:exactMatchuniprot-protein:O95833lld:mappings
cpath:CPATH-97186skos:closeMatchentrez-gene:9022lld:mappings
cpath:CPATH-LOCAL-11436909http://www.biopax.org/relea...cpath:CPATH-97186lld:biogrid