| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-4063,
cpath:CPATH-LOCAL-4064,
cpath:CPATH-LOCAL-4065,
cpath:CPATH-LOCAL-4066,
cpath:CPATH-LOCAL-4067,
cpath:CPATH-LOCAL-4068,
cpath:CPATH-LOCAL-4069,
cpath:CPATH-LOCAL-4070,
cpath:CPATH-LOCAL-4071,
cpath:CPATH-LOCAL-4072,
cpath:CPATH-LOCAL-4073,
cpath:CPATH-LOCAL-4074,
cpath:CPATH-LOCAL-9581
|
| http://www.biopax.org/relea... |
Cyclin-T2
|
| http://www.biopax.org/relea... |
CCNT2_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CycT2
|
| http://www.biopax.org/relea... |
FUNCTION: Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II). SUBUNIT: Associates with CDK9 to form P-TEFb. Isoform 1 and isoform 2 interact with HIV-2 and SIV Tat. Does not bind efficiently to the transactivation domain of the HIV-1 Tat. SUBCELLULAR LOCATION: Nucleus. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; Synonyms=B; IsoId=O60583-1; Sequence=Displayed; Name=2; Synonyms=A; IsoId=O60583-2; Sequence=VSP_001258; Note=Phosphorylated on Ser-663; TISSUE SPECIFICITY: Ubiquitously expressed. SIMILARITY: Belongs to the cyclin family. Cyclin C subfamily. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/ccnt2/"; COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |