| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-4049,
cpath:CPATH-LOCAL-4050,
cpath:CPATH-LOCAL-4051,
cpath:CPATH-LOCAL-4052,
cpath:CPATH-LOCAL-4053,
cpath:CPATH-LOCAL-4054,
cpath:CPATH-LOCAL-4055,
cpath:CPATH-LOCAL-4056,
cpath:CPATH-LOCAL-4057,
cpath:CPATH-LOCAL-4058,
cpath:CPATH-LOCAL-4059,
cpath:CPATH-LOCAL-4060,
cpath:CPATH-LOCAL-9580
|
| http://www.biopax.org/relea... |
T-cell-specific surface glycoprotein CD28
|
| http://www.biopax.org/relea... |
CD28_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CD28,
TP44
|
| http://www.biopax.org/relea... |
FUNCTION: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. SUBUNIT: Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=6; Name=1; IsoId=P10747-1; Sequence=Displayed; Name=2; Synonyms=CD28-S2; IsoId=P10747-2; Sequence=VSP_002494; Name=3; Synonyms=CD28i; IsoId=P10747-3; Sequence=VSP_002495; Name=4; Synonyms=CD28-S1; IsoId=P10747-4; Sequence=VSP_002496; Name=5; IsoId=P10747-5; Sequence=VSP_002495, VSP_002497, VSP_002498; Name=6; Synonyms=CD28-S3; IsoId=P10747-6; Sequence=VSP_002495, VSP_002499; TISSUE SPECIFICITY: Expressed in T-cells and plasma cells, but not in less mature B-cells. SIMILARITY: Contains 1 Ig-like V-type (immunoglobulin-like) domain. WEB RESOURCE: Name=Wikipedia; Note=CD28 entry; URL="http://en.wikipedia.org/wiki/CD28"; COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |