Statements in which the resource exists as a subject.
PredicateObject
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http://www.biopax.org/relea...
http://www.biopax.org/relea...
Calumenin
http://www.biopax.org/relea...
CALU_HUMAN
http://www.biopax.org/relea...
http://www.biopax.org/relea...
Crocalbin, IEF SSP 9302
http://www.biopax.org/relea...
FUNCTION: Involved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity). SUBUNIT: Interacts with GGCX (By similarity). SUBCELLULAR LOCATION: Endoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen (By similarity). Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=O43852-1; Sequence=Displayed; Name=2; IsoId=O43852-2; Sequence=VSP_007317; TISSUE SPECIFICITY: Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver. SIMILARITY: Belongs to the CREC family. SIMILARITY: Contains 6 EF-hand domains. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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