| Predicate | Object |
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| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Tethering factor for nuclear proteasome cut8
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| http://www.biopax.org/relea... |
CUT8_SCHPO
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Cell untimely torn protein 8
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| http://www.biopax.org/relea... |
FUNCTION: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins like mitotic cyclin and cut2. Required for normal progression of anaphase. SUBUNIT: Binds the proteasome. SUBCELLULAR LOCATION: Nucleus. PTM: The N-terminal part (residues 1 to 72) is polyubiquitinated by rhp6, which is required for the interaction with the proteasome. SIMILARITY: Belongs to the cut8/STS1 family. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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