| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Probable histone acetyltransferase MYST1
|
| http://www.biopax.org/relea... |
MYST1_MOUSE
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
2.3.1.48,
MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1,
MYST-1
|
| http://www.biopax.org/relea... |
FUNCTION: Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM (By similarity). CATALYTIC ACTIVITY: Acetyl-CoA + [histone] = CoA + acetyl- [histone]. SUBUNIT: Component of a multisubunit histone acetyltransferase complex (MSL) at least composed of the MOF/MYST1, MSL1/hampin, MSL2L1 and MSL3L1. Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components C17orf49, CHD8, E2F6, HSP70, IN80C, KIAA1267, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with the chromodomain of MORF4L1/MRG15. Interacts with ATM through the chromodomain (By similarity). SUBCELLULAR LOCATION: Nucleus (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9D1P2-1; Sequence=Displayed; Name=2; IsoId=Q9D1P2-2; Sequence=VSP_014580, VSP_014581; SIMILARITY: Belongs to the MYST (SAS/MOZ) family. SIMILARITY: Contains 1 C2HC-type zinc finger. SIMILARITY: Contains 1 chromo domain. SEQUENCE CAUTION: Sequence=BAC25539.1; Type=Frameshift; Positions=236; GENE SYNONYMS: Mof. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| skos:exactMatch | |
| skos:closeMatch |