| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
C-C motif chemokine 23
|
| http://www.biopax.org/relea... |
CCL23_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CCL23(19-99),
CCL23(22-99),
CCL23(27-99),
CCL23(30-99),
CK-beta-8,
CKB-8,
MIP-3,
MPIF-1,
Macrophage inflammatory protein 3,
Myeloid progenitor inhibitory factor 1,
Small-inducible cytokine A23
|
| http://www.biopax.org/relea... |
FUNCTION: Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. SUBCELLULAR LOCATION: Secreted. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=Short; Synonyms=CKB-8; IsoId=P55773-1; Sequence=Displayed; Name=Long; Synonyms=CKB-8-1; IsoId=P55773-2; Sequence=VSP_001063; TISSUE SPECIFICITY: High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients. SIMILARITY: Belongs to the intercrine beta (chemokine CC) family. WEB RESOURCE: Name=Wikipedia; Note=CCL23 entry; URL="http://en.wikipedia.org/wiki/CCL23"; GENE SYNONYMS: MIP3 MPIF1 SCYA23. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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