| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Centrosomal protein of 76 kDa
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| http://www.biopax.org/relea... |
CEP76_HUMAN
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Cep76
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| http://www.biopax.org/relea... |
FUNCTION: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication. SUBUNIT: Interacts with CEP110/CP110 and CEP97. SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, centrosome, centriole. Note=Does not localize along the ciliary axoneme. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8TAP6-1; Sequence=Displayed; Name=2; IsoId=Q8TAP6-2; Sequence=VSP_037611; Note=No experimental confirmation available; Name=3; IsoId=Q8TAP6-3; Sequence=VSP_037610, VSP_037612, VSP_037613; Note=No experimental confirmation available; DEVELOPMENTAL STAGE: Expressed at low level in G1 and is induced in S and G2 phase, during which point centrioles have already commenced duplication (at protein level). SIMILARITY: Belongs to the CEP76 family. SEQUENCE CAUTION: Sequence=BAG64223.1; Type=Erroneous termination; Positions=648; Note=Translated as Trp; GENE SYNONYMS: C18orf9. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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