| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-300691,
cpath:CPATH-LOCAL-300691,
cpath:CPATH-LOCAL-300692,
cpath:CPATH-LOCAL-300692,
cpath:CPATH-LOCAL-300693,
cpath:CPATH-LOCAL-300693,
cpath:CPATH-LOCAL-300694,
cpath:CPATH-LOCAL-300694,
cpath:CPATH-LOCAL-300695,
cpath:CPATH-LOCAL-300695,
cpath:CPATH-LOCAL-300696,
cpath:CPATH-LOCAL-300696,
cpath:CPATH-LOCAL-300697,
cpath:CPATH-LOCAL-300697,
cpath:CPATH-LOCAL-300698,
cpath:CPATH-LOCAL-300698,
cpath:CPATH-LOCAL-300699,
cpath:CPATH-LOCAL-300699,
cpath:CPATH-LOCAL-300700,
cpath:CPATH-LOCAL-300700,
cpath:CPATH-LOCAL-300701,
cpath:CPATH-LOCAL-300701,
cpath:CPATH-LOCAL-303927,
cpath:CPATH-LOCAL-303927
|
| http://www.biopax.org/relea... |
RING finger and CHY zinc finger domain-containing protein 1,
RING finger and CHY zinc finger domain-containing protein 1
|
| http://www.biopax.org/relea... |
ZN363_HUMAN,
ZN363_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
6.3.2.-,
6.3.2.-,
Androgen receptor N-terminal-interacting protein,
Androgen receptor N-terminal-interacting protein,
CH-rich-interacting match with PLAG1,
CH-rich-interacting match with PLAG1,
E3 ubiquitin-protein ligase Pirh2,
E3 ubiquitin-protein ligase Pirh2,
RING finger protein 199,
RING finger protein 199,
Zinc finger protein 363,
Zinc finger protein 363,
hPirh2,
hPirh2,
p53-induced RING-H2 protein,
p53-induced RING-H2 protein
|
| http://www.biopax.org/relea... |
FUNCTION: Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Contributes to the regulation of CDKN1B and p53/TP53 levels, and thereby contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity. PATHWAY: Protein modification; protein ubiquitination. SUBUNIT: Monomer and homodimer. Interacts with AR, p53/TP53, MDM2, HDAC1, KAT5, PLAG1, PLAGL2, CDKN1B, UBE2D2 and GORAB/NTKLBP1. SUBCELLULAR LOCATION: Nucleus. Nucleus speckle. Cytoplasm. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=A; IsoId=Q96PM5-1; Sequence=Displayed; Name=2; Synonyms=B; IsoId=Q96PM5-2; Sequence=VSP_038467; Name=3; Synonyms=C; IsoId=Q96PM5-3; Sequence=VSP_038468; INDUCTION: Up-regulated during the S phase of the cell cycle. Expressed at low levels during G phase. PTM: Subject to ubiquitination and proteasomal degradation. Interaction with PLAGL2 or KAT5 enhances protein stability. SIMILARITY: Contains 1 CHY-type zinc finger. SIMILARITY: Contains 1 CTCHY-type zinc finger. SIMILARITY: Contains 1 RING-type zinc finger. SEQUENCE CAUTION: Sequence=BAD92309.1; Type=Erroneous initiation; WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/RCHY1ID43012ch04q21.html"; GENE SYNONYMS: ARNIP CHIMP PIRH2 RNF199 ZNF363. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
FUNCTION: Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Contributes to the regulation of CDKN1B and p53/TP53 levels, and thereby contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity. PATHWAY: Protein modification; protein ubiquitination. SUBUNIT: Monomer and homodimer. Interacts with AR, p53/TP53, MDM2, HDAC1, KAT5, PLAG1, PLAGL2, CDKN1B, UBE2D2 and GORAB/NTKLBP1. SUBCELLULAR LOCATION: Nucleus. Nucleus speckle. Cytoplasm. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=A; IsoId=Q96PM5-1; Sequence=Displayed; Name=2; Synonyms=B; IsoId=Q96PM5-2; Sequence=VSP_038467; Name=3; Synonyms=C; IsoId=Q96PM5-3; Sequence=VSP_038468; INDUCTION: Up-regulated during the S phase of the cell cycle. Expressed at low levels during G phase. PTM: Subject to ubiquitination and proteasomal degradation. Interaction with PLAGL2 or KAT5 enhances protein stability. SIMILARITY: Contains 1 CHY-type zinc finger. SIMILARITY: Contains 1 CTCHY-type zinc finger. SIMILARITY: Contains 1 RING-type zinc finger. SEQUENCE CAUTION: Sequence=BAD92309.1; Type=Erroneous initiation; WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/RCHY1ID43012ch04q21.html"; GENE SYNONYMS: ARNIP CHIMP PIRH2 RNF199 ZNF363. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |