Linked Life Data

CPATH-68198

Source:http://cbio.mskcc.org/cpath#CPATH-68198

Statements in which the resource exists.
SubjectPredicateObjectContext
cpath:CPATH-68198rdf:typehttp://www.biopax.org/relea...lld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...cpath:CPATH-LOCAL-282081lld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...cpath:CPATH-LOCAL-282082lld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...cpath:CPATH-LOCAL-282083lld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...cpath:CPATH-LOCAL-282084lld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...cpath:CPATH-LOCAL-286757lld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...Cyclin-dependent kinase 5lld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...CDK5_RATlld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...cpath:CPATH-LOCAL-282079lld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...2.7.11.22lld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...TPKII catalytic subunitlld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...Serine/threonine-protein kinase PSSALRElld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...Tau protein kinase II catalytic subunitlld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...Cell division protein kinase 5lld:biogrid
cpath:CPATH-68198http://www.biopax.org/relea...FUNCTION: Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase. CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. SUBUNIT: Heterodimer of a catalytic subunit and a regulatory subunit (p35). Found in a trimolecular complex with CABLES1 and ABL1. Interacts with CABLES1 (By similarity). Interacts with AATK. SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell projection, lamellipodium (By similarity). Cell projection, growth cone (By similarity). Note=In axonal growth cone with extension to the peripheral lamellipodia (By similarity). TISSUE SPECIFICITY: Expressed predominantly in post-mitotic neurons of the central and peripheral nervous system. SIMILARITY: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. SIMILARITY: Contains 1 protein kinase domain. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
cpath:CPATH-68198skos:exactMatchuniprot-protein:Q03114lld:mappings
cpath:CPATH-68198skos:closeMatchentrez-gene:140908lld:mappings
cpath:CPATH-LOCAL-7823457http://www.biopax.org/relea...cpath:CPATH-68198lld:biogrid