| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Phosphatidate cytidylyltransferase 1
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| http://www.biopax.org/relea... |
CDS1_HUMAN
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
2.7.7.41,
CDP-DAG synthase 1,
CDP-DG synthase 1,
CDP-diacylglycerol synthase 1,
CDP-diglyceride pyrophosphorylase 1,
CDP-diglyceride synthase 1,
CDS 1,
CTP:phosphatidate cytidylyltransferase 1
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| http://www.biopax.org/relea... |
FUNCTION: Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells. CATALYTIC ACTIVITY: CTP + phosphatidate = diphosphate + CDP- diacylglycerol. COFACTOR: Magnesium (By similarity). PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Note=Cytoplasmic aspect of the endoplasmic reticulum (By similarity). TISSUE SPECIFICITY: Expressed in adult tissues such as placenta, brain, small intestine, ovary, testis and prostate. Highly expressed in fetal kidney, lung and brain. Lower level in fetal liver. SIMILARITY: Belongs to the CDS family. GENE SYNONYMS: CDS. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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