| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Type I inositol-1,4,5-trisphosphate 5-phosphatase
|
| http://www.biopax.org/relea... |
I5P1_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
3.1.3.56,
5PTase
|
| http://www.biopax.org/relea... |
FUNCTION: Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction. CATALYTIC ACTIVITY: D-myo-inositol 1,4,5-trisphosphate + H(2)O = myo-inositol 1,4-bisphosphate + phosphate. CATALYTIC ACTIVITY: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H(2)O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate. SUBCELLULAR LOCATION: Membrane; Lipid-anchor. TISSUE SPECIFICITY: Brain; high level in Purkinje cells. SIMILARITY: Belongs to the inositol-1,4,5-trisphosphate 5- phosphatase type I family. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| skos:exactMatch | |
| skos:closeMatch |