| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-2672,
cpath:CPATH-LOCAL-2672,
cpath:CPATH-LOCAL-2673,
cpath:CPATH-LOCAL-2673,
cpath:CPATH-LOCAL-2674,
cpath:CPATH-LOCAL-2674,
cpath:CPATH-LOCAL-2675,
cpath:CPATH-LOCAL-2675,
cpath:CPATH-LOCAL-2676,
cpath:CPATH-LOCAL-2676,
cpath:CPATH-LOCAL-2677,
cpath:CPATH-LOCAL-2677,
cpath:CPATH-LOCAL-2678,
cpath:CPATH-LOCAL-2678,
cpath:CPATH-LOCAL-2679,
cpath:CPATH-LOCAL-2679,
cpath:CPATH-LOCAL-2680,
cpath:CPATH-LOCAL-2680,
cpath:CPATH-LOCAL-2681,
cpath:CPATH-LOCAL-2681,
cpath:CPATH-LOCAL-2682,
cpath:CPATH-LOCAL-2682,
cpath:CPATH-LOCAL-9423,
cpath:CPATH-LOCAL-9423
|
| http://www.biopax.org/relea... |
CD151 antigen,
CD151 antigen
|
| http://www.biopax.org/relea... |
CD151_HUMAN,
CD151_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CD151,
CD151,
GP27,
GP27,
Membrane glycoprotein SFA-1,
Membrane glycoprotein SFA-1,
PETA-3,
PETA-3,
Platelet-endothelial tetraspan antigen 3,
Platelet-endothelial tetraspan antigen 3,
Tetraspanin-24,
Tetraspanin-24,
Tspan-24,
Tspan-24
|
| http://www.biopax.org/relea... |
FUNCTION: Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. SUBUNIT: Interacts with integrins alpha3beta1, alpha5beta1, alpha3beta1 and alpha6beta4, with CD9 and CD181. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in a variety of tissues including vascular endothelium and epidermis. Expressed on erythroid cells, with a higher level of expression in erythroid precursors than on mature erythrocytes. INDUCTION: By HTLV-1. POLYMORPHISM: CD151 defines the MER2=RAPH1 antigen of the RAPH blood group system. 92% of Caucasians are MER2-positive and 8% are apparently MER2-negative. DISEASE: Defects in CD151 are the cause of nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD) [MIM:609057]. NPEBD is characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor. SIMILARITY: Belongs to the tetraspanin (TM4SF) family. WEB RESOURCE: Name=dbRBC/BGMUT; Note=Blood group antigen gene mutation database; URL="http://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/systems_info&system=raph"; WEB RESOURCE: Name=SeattleSNPs; URL="http://pga.gs.washington.edu/data/cd151/"; GENE SYNONYMS: TSPAN24. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
FUNCTION: Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. SUBUNIT: Interacts with integrins alpha3beta1, alpha5beta1, alpha3beta1 and alpha6beta4, with CD9 and CD181. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in a variety of tissues including vascular endothelium and epidermis. Expressed on erythroid cells, with a higher level of expression in erythroid precursors than on mature erythrocytes. INDUCTION: By HTLV-1. POLYMORPHISM: CD151 defines the MER2=RAPH1 antigen of the RAPH blood group system. 92% of Caucasians are MER2-positive and 8% are apparently MER2-negative. DISEASE: Defects in CD151 are the cause of nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD) [MIM:609057]. NPEBD is characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor. SIMILARITY: Belongs to the tetraspanin (TM4SF) family. WEB RESOURCE: Name=dbRBC/BGMUT; Note=Blood group antigen gene mutation database; URL="http://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/systems_info&system=raph"; WEB RESOURCE: Name=SeattleSNPs; URL="http://pga.gs.washington.edu/data/cd151/"; GENE SYNONYMS: TSPAN24. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |