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Eukaryotic translation initiation factor 3 subunit G
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EIF3G_YEAST
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Eukaryotic translation initiation factor 3 RNA-binding subunit, Translation initiation factor eIF3 p33 subunit, eIF-3 RNA-binding subunit, eIF3 p33, eIF3g
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FUNCTION: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. TIF35 binds to mRNA and rRNA. Binds to the 18S rRNA but non-specifically. SUBUNIT: The eukaryotic translation initiation factor 3 (eIF-3) core complex is composed of TIF32, PRT1, NIP1, TIF34 and TIF35. The factors eIF-1, eIF-2, eIF-3, TIF5/eIF-5 and methionyl-tRNAi form a multifactor complex (MFC) that may bind to the 40S ribosome. SUBCELLULAR LOCATION: Cytoplasm (Probable). SIMILARITY: Belongs to the eIF-3 subunit G family. SIMILARITY: Contains 1 RRM (RNA recognition motif) domain. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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