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http://www.biopax.org/relea... | |
http://www.biopax.org/relea... |
WASH complex subunit CCDC53
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http://www.biopax.org/relea... |
CCD53_HUMAN
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http://www.biopax.org/relea... | |
http://www.biopax.org/relea... |
Coiled-coil domain-containing protein 53
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http://www.biopax.org/relea... |
FUNCTION: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. SUBUNIT: Component of the WASH complex, composed of F-actin- capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin- capping protein subunit beta (CAPZB), WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P), FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033, KIAA0196 and CCDC53. SIMILARITY: Belongs to the CCDC53 family. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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