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rdf:type |
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http://www.biopax.org/relea... |
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http://www.biopax.org/relea... |
ID
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http://www.biopax.org/relea... |
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http://www.biopax.org/relea... |
cpath:CPATH-544926,
cpath:CPATH-544927,
cpath:CPATH-544928,
cpath:CPATH-544929,
cpath:CPATH-544930,
cpath:CPATH-544931,
cpath:CPATH-544932,
cpath:CPATH-544933,
cpath:CPATH-544934,
cpath:CPATH-544935,
cpath:CPATH-544936,
cpath:CPATH-544937,
cpath:CPATH-544938,
cpath:CPATH-544939,
cpath:CPATH-544940,
cpath:CPATH-544941,
cpath:CPATH-544942,
cpath:CPATH-544943,
cpath:CPATH-544944,
cpath:CPATH-544945,
cpath:CPATH-544946,
cpath:CPATH-544947,
cpath:CPATH-544948,
cpath:CPATH-544949,
cpath:CPATH-544950,
cpath:CPATH-544951,
cpath:CPATH-544952,
cpath:CPATH-544953,
cpath:CPATH-544954,
cpath:CPATH-544955,
cpath:CPATH-544956,
cpath:CPATH-544957,
cpath:CPATH-544958,
cpath:CPATH-544959,
cpath:CPATH-544960,
cpath:CPATH-544961,
cpath:CPATH-544962,
cpath:CPATH-544963,
cpath:CPATH-544964,
cpath:CPATH-544965,
cpath:CPATH-544966,
cpath:CPATH-544967,
cpath:CPATH-544968,
cpath:CPATH-544969,
cpath:CPATH-544970,
cpath:CPATH-544971,
cpath:CPATH-544972,
cpath:CPATH-544973,
cpath:CPATH-544974,
cpath:CPATH-544975,
cpath:CPATH-544976,
cpath:CPATH-544977,
cpath:CPATH-544978,
cpath:CPATH-544979,
cpath:CPATH-544980,
cpath:CPATH-544981,
cpath:CPATH-544982,
cpath:CPATH-544983,
cpath:CPATH-544984
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http://www.biopax.org/relea... |
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http://www.biopax.org/relea... |
Freely available from The Cancer Cell Map (created by Memorial Sloan-Kettering Cancer Center and the Institute of Bioinformatics) under the Creative Commons license (http://creativecommons.org/licenses/by/2.5/)
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http://www.biopax.org/relea... |
Id Proteins are members of the basic HLH(helix-loop-helix ) family of transcription factors but lack a DNA binding domain. The Id family of proteins comprises of 4 members designated Id1-Id4.They have been demonstrated to bind the ubiquitously expressed bHLH E-proteins or cell lineage-restricted bHLH transcription factors, leading to inhibition of lineage-specific gene expression and differentiation.Hence, the name Id refers to both inhibition of differentiation and inhibition of DNA binding.Id proteins have been implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation.
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