CPATH-543792

Source:http://cbio.mskcc.org/cpath#CPATH-543792

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Named Graph Language Inference

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	http://www.biopax.org/release/biopax-level2.owl#catalysis
http://www.biopax.org/relea...	cpath:CPATH-LOCAL-7760520, cpath:CPATH-LOCAL-7765774
http://www.biopax.org/relea...	Ub-BTRC-p105
http://www.biopax.org/relea...	cpath:CPATH-543793
http://www.biopax.org/relea...	cpath:CPATH-LOCAL-7760524
http://www.biopax.org/relea...	PHYSIOL-LEFT-TO-RIGHT
http://www.biopax.org/relea...	cpath:CPATH-LOCAL-7760521
http://www.biopax.org/relea...	Ubiquitination of p105 by BTRC.1) BTRC associates physically with phosphorylated p105 strongly support the notion that signaling plays an important role in p105 processing/degradation that results in enhanced transcription.2) When substituted serine residues 922, 924 and 933 with alanine in p105,the ability of BTRC to catalyze conjugation is abolished, strongly suggesting that these residues are targeted by the kinase.