| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Ap-TBK1-TBK1
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
PHYSIOL-LEFT-TO-RIGHT
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Autophosphorylation of TBK11) TBK1 play an important role in the signaling pathways by which extracellular stimuli such as platelet-derived growth factor and TNF-alpha activate NF-kB.2) NAP1 binding stimulated the autophosphorylation of TBK1.Binding of NAP1 to TBK1 may induce NAK oligomerization which might affect both the kinase activity of TBK1 and its substrate specificity, as NAP1 binding stimulated the autophosphorylation of TBK1.3) Myc-TBK1 immunoprecipitated from transfected insect Sf9 cells was used for the in vitro assay.
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