Predicate | Object |
---|---|
rdf:type | |
http://www.biopax.org/relea... | |
http://www.biopax.org/relea... |
Ub-BTRC-IKBB
|
http://www.biopax.org/relea... | |
http://www.biopax.org/relea... | |
http://www.biopax.org/relea... |
PHYSIOL-LEFT-TO-RIGHT
|
http://www.biopax.org/relea... | |
http://www.biopax.org/relea... |
Ubiquitination of IKBB by BTRC.1)BTRC promotes the ubiquitination of phosphorylated IKBB and activates NF-KappaB.2)Beta -TrCP is a component of the ubiquitin ligase for Ikappa B proteins, and the signal-induced phosphorylation of Ikappa Bbeta by IKKs is a critical step that precedes their ubiquitination and degradation.
|