| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-22283,
cpath:CPATH-LOCAL-22283,
cpath:CPATH-LOCAL-22284,
cpath:CPATH-LOCAL-22284,
cpath:CPATH-LOCAL-22285,
cpath:CPATH-LOCAL-22285,
cpath:CPATH-LOCAL-22286,
cpath:CPATH-LOCAL-22286,
cpath:CPATH-LOCAL-22287,
cpath:CPATH-LOCAL-22287,
cpath:CPATH-LOCAL-22288,
cpath:CPATH-LOCAL-22288,
cpath:CPATH-LOCAL-27063,
cpath:CPATH-LOCAL-27063
|
| http://www.biopax.org/relea... |
Cytokine receptor common subunit beta,
Cytokine receptor common subunit beta
|
| http://www.biopax.org/relea... |
IL3RB_HUMAN,
IL3RB_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CD131,
CD131,
CDw131,
CDw131,
GM-CSF/IL-3/IL-5 receptor common beta subunit,
GM-CSF/IL-3/IL-5 receptor common beta subunit
|
| http://www.biopax.org/relea... |
FUNCTION: High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. SUBUNIT: Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. Interacts with TMEM102; this interaction occurs preferentially in the absence of CSF2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P32927-1; Sequence=Displayed; Name=2; IsoId=P32927-2; Sequence=VSP_032798; DOMAIN: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell- surface receptor binding. DOMAIN: The box 1 motif is required for JAK interaction and/or activation. SIMILARITY: Belongs to the type I cytokine receptor family. Type 4 subfamily. SIMILARITY: Contains 2 fibronectin type-III domains. GENE SYNONYMS: IL3RB IL5RB. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
FUNCTION: High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. SUBUNIT: Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. Interacts with TMEM102; this interaction occurs preferentially in the absence of CSF2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P32927-1; Sequence=Displayed; Name=2; IsoId=P32927-2; Sequence=VSP_032798; DOMAIN: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell- surface receptor binding. DOMAIN: The box 1 motif is required for JAK interaction and/or activation. SIMILARITY: Belongs to the type I cytokine receptor family. Type 4 subfamily. SIMILARITY: Contains 2 fibronectin type-III domains. GENE SYNONYMS: IL3RB IL5RB. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| skos:exactMatch | |
| skos:closeMatch |