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http://www.biopax.org/relea... | |
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CTP synthase 2
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http://www.biopax.org/relea... |
PYRG2_HUMAN
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http://www.biopax.org/relea... | |
http://www.biopax.org/relea... |
6.3.4.2,
CTP synthetase 2,
UTP--ammonia ligase 2
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http://www.biopax.org/relea... |
FUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. CATALYTIC ACTIVITY: ATP + UTP + NH(3) = ADP + phosphate + CTP. PATHWAY: Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2. SIMILARITY: Belongs to the CTP synthase family. SIMILARITY: Contains 1 glutamine amidotransferase type-1 domain. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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