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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Cholecystokinin receptor type A
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| http://www.biopax.org/relea... |
CCKAR_HUMAN
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CCK-A receptor,
CCK-AR,
CCK1-R,
Cholecystokinin-1 receptor
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| http://www.biopax.org/relea... |
FUNCTION: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. SIMILARITY: Belongs to the G-protein coupled receptor 1 family. WEB RESOURCE: Name=Wikipedia; Note=Cholecystokinin receptor entry; URL="http://en.wikipedia.org/wiki/Cholecystokinin_receptor"; GENE SYNONYMS: CCKRA. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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