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http://www.biopax.org/relea...
http://www.biopax.org/relea...
AP-2 complex subunit sigma
http://www.biopax.org/relea...
AP2S_YEAST
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http://www.biopax.org/relea...
Adaptin small chain, Clathrin assembly protein 2 small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin
http://www.biopax.org/relea...
FUNCTION: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. SUBUNIT: Assembly protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit APL3 and beta- type subunit APL1), a medium chain (mu-type subunit APM4) and a small adaptin (sigma-type subunit APS2). Interacts with APL1. SUBCELLULAR LOCATION: Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of the plasma membrane coated vesicles. MISCELLANEOUS: Present with 1390 molecules/cell in log phase SD medium. SIMILARITY: Belongs to the adaptor complexes small subunit family. GENE SYNONYMS: YAP17. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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