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Geranylgeranyl transferase type-1 subunit beta
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PGTB1_SCHPO
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2.5.1.59, GGTase-I-beta, Geranylgeranyl transferase type I subunit beta, PGGT, Type I protein geranyl-geranyltransferase subunit beta
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FUNCTION: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal C- A-A-L where A is an aliphatic amino acid. In particular it modifies the GTP-binding component of the 1,3-beta-D-glucan synthase. CATALYTIC ACTIVITY: Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. COFACTOR: Binds 1 zinc ion per subunit (By similarity). SUBUNIT: Heterodimer of an alpha and a beta subunit. SIMILARITY: Belongs to the protein prenyltransferase subunit beta family. SIMILARITY: Contains 4 PFTB repeats. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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