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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
COMPASS component SWD2
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| http://www.biopax.org/relea... |
SWD2_YEAST
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Complex proteins associated with SET1 protein SWD2,
Set1C component SWD2
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| http://www.biopax.org/relea... |
FUNCTION: The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. FUNCTION: Involved in mediating RNA polymerase II termination. Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre- mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation. SUBUNIT: Component of the COMPASS (Set1C) complex which consists of SET1(2), BRE2(2), SPP1(2), SDC1(1), SHG1(1), SWD1(1), SWD2(1), and SWD3(1). Component of the cleavage and polyadenylation factor (CPF) complex, which is composed of PTI1, SYC1, SSU72, GLC7, MPE1, REF2, PFS2, PTA1, YSH1/BRR5, SWD2, CFT2/YDH1, YTH1, CFT1/YHH1, FIP1 and PAP1. Component of the APT complex, which is a subcomplex of CPF, and is composed of PTI1, SYC1, SSU72, GLC7, REF2, PTA1 and SWD2. SUBCELLULAR LOCATION: Nucleus. Chromosome, telomere. MISCELLANEOUS: Present with 704 molecules/cell in log phase SD medium. SIMILARITY: Belongs to the WD repeat SWD2 family. SIMILARITY: Contains 6 WD repeats. GENE SYNONYMS: CPS35 SAF37. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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