Linked Life Data

CPATH-34041

Source:http://cbio.mskcc.org/cpath#CPATH-34041

Statements in which the resource exists.
SubjectPredicateObjectContext
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cpath:CPATH-34041http://www.biopax.org/relea...Single-stranded nucleic acid-binding proteinlld:biogrid
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cpath:CPATH-34041http://www.biopax.org/relea...FUNCTION: Functions in the transition of mRNAs from translation to an mRNP complex destined for decapping. High-copy-number suppressor of decapping defects. Overexpression suppresses decapping defects in both DCP1-2 and DCP2-7 mutations. Acts to promote translational repression of mRNA in conjunction with DHH1 and subsequent mRNA localization to P bodies. Promotes translational repression of mRNA during glucose deprivation. SUBUNIT: Associated with snR10 and snR11 small nuclear RNAs. SUBCELLULAR LOCATION: Cytoplasm. Nucleus, nucleolus. Note=Found in cytoplasmic P bodies. MISCELLANEOUS: Present with 12800 molecules/cell in log phase SD medium. SIMILARITY: Belongs to the RRM GAR family. SIMILARITY: Contains 2 RRM (RNA recognition motif) domains. SEQUENCE CAUTION: Sequence=AAA35098.1; Type=Frameshift; Positions=162, 175, 181; GENE SYNONYMS: SSB1 SSBR1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
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