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http://www.biopax.org/relea...
http://www.biopax.org/relea...
DNA damage-inducible transcript 4-like protein
http://www.biopax.org/relea...
DDT4L_HUMAN
http://www.biopax.org/relea...
http://www.biopax.org/relea...
HIF-1 responsive protein RTP801-like, Protein regulated in development and DNA damage response 2, REDD-2
http://www.biopax.org/relea...
FUNCTION: Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. SUBCELLULAR LOCATION: Cytoplasm (By similarity). TISSUE SPECIFICITY: Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery. INDUCTION: Up-regulated by oxidized LDL and hypoxia in macrophages. SIMILARITY: Belongs to the DDIT4 family. GENE SYNONYMS: REDD2 RTP801L. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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