| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
C-C motif chemokine 21
|
| http://www.biopax.org/relea... |
CCL21_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
6Ckine,
Beta-chemokine exodus-2,
SLC,
Secondary lymphoid-tissue chemokine,
Small-inducible cytokine A21
|
| http://www.biopax.org/relea... |
FUNCTION: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. SUBUNIT: Binds to CCR7. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen. SIMILARITY: Belongs to the intercrine beta (chemokine CC) family. WEB RESOURCE: Name=Wikipedia; Note=CCL21 entry; URL="http://en.wikipedia.org/wiki/CCL21"; GENE SYNONYMS: SCYA21. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |