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rdf:type | |
http://www.biopax.org/relea... | |
http://www.biopax.org/relea... |
Deleted in azoospermia-like
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http://www.biopax.org/relea... |
DAZL_HUMAN
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http://www.biopax.org/relea... | |
http://www.biopax.org/relea... |
DAZ homolog,
DAZ-like autosomal,
Deleted in azoospermia-like 1,
SPGY-like-autosomal
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http://www.biopax.org/relea... |
FUNCTION: RNA-binding protein, which is essential for gametogenesis. Plays a central role during spermatogenesis. May act by binding to the 3'-UTR of mRNA and thereby regulating the translation of key transcripts (By similarity). SUBUNIT: Homodimer and heterodimer (By similarity). Forms a heterodimer with DAZ. Interacts with BOLL, DAZAP1 and DAZAP2. Interacts with PUM2. SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By similarity). Note=Predominantly cytoplasmic (By similarity). Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward (By similarity). TISSUE SPECIFICITY: Testis specific. DOMAIN: The DAZ-like domain mediates the interaction with DAZAP1 and DAZAP2. SIMILARITY: Belongs to the RRM DAZ family. SIMILARITY: Contains 1 DAZ-like domain. SIMILARITY: Contains 1 RRM (RNA recognition motif) domain. GENE SYNONYMS: DAZH DAZL1 DAZLA SPGYLA. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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