| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
C-C motif chemokine 17
|
| http://www.biopax.org/relea... |
CCL17_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CC chemokine TARC,
Small-inducible cytokine A17,
Thymus and activation-regulated chemokine
|
| http://www.biopax.org/relea... |
FUNCTION: Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Expressed at high levels in thymus and at low levels in the lung, colon and small intestine. INDUCTION: By phytohemagglutinin (PHA) in the peripheral blood mononuclear cells and by cytokines in monocytes. SIMILARITY: Belongs to the intercrine beta (chemokine CC) family. CAUTION: Was originally (PubMed:9521068) thought to be a ligand for CCR8. WEB RESOURCE: Name=Wikipedia; Note=CCL17 entry; URL="http://en.wikipedia.org/wiki/CCL17"; GENE SYNONYMS: SCYA17 TARC. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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