| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Cyclin-dependent kinase 1
|
| http://www.biopax.org/relea... |
CDK1_YEAST
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
2.7.11.22,
CDK1,
Cell division control protein 28,
Cell division protein kinase 1
|
| http://www.biopax.org/relea... |
FUNCTION: This protein is essential for the completion of the start, the controlling event, in the cell cycle. More than 200 substrates have been identified. CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. ENZYME REGULATION: Phosphorylation at Thr-18 or Tyr-19 inactivates the enzyme, while phosphorylation at Thr-169 activates it (By similarity). SUBUNIT: Forms a stable but non-covalent complex with the CKS1 protein and with a cyclin. MISCELLANEOUS: Present with 6670 molecules/cell in log phase SD medium. SIMILARITY: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. SIMILARITY: Contains 1 protein kinase domain. GENE SYNONYMS: CDK1 HSL5 SRM5. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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