| Predicate | Object |
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Ketol-acid reductoisomerase, mitochondrial
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| http://www.biopax.org/relea... |
ILV5_YEAST
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
1.1.1.86,
Acetohydroxy-acid reductoisomerase,
Alpha-keto-beta-hydroxylacil reductoisomerase
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| http://www.biopax.org/relea... |
CATALYTIC ACTIVITY: (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH. CATALYTIC ACTIVITY: (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-hydroxy-2-ethyl-3-oxobutanoate + NADPH. COFACTOR: Binds 2 magnesium ions per subunit (By similarity). PATHWAY: Amino-acid biosynthesis; L-isoleucine biosynthesis; L- isoleucine from 2-oxobutanoate: step 2/4. PATHWAY: Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4. SUBCELLULAR LOCATION: Mitochondrion. MISCELLANEOUS: Present with 883000 molecules/cell in log phase SD medium. SIMILARITY: Belongs to the ketol-acid reductoisomerase family. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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