| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Neurofilament light polypeptide
|
| http://www.biopax.org/relea... |
NFL_MOUSE
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
68 kDa neurofilament protein,
NF-L,
Neurofilament triplet L protein
|
| http://www.biopax.org/relea... |
FUNCTION: Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. SUBUNIT: Interacts with RGNEF. DOMAIN: The extra mass and high charge density that distinguish the neurofilament proteins from all other intermediate filament proteins are due to the tailpiece extensions. This region may form a charged scaffolding structure suitable for interaction with other neuronal components or ions. PTM: O-glycosylated. PTM: Phosphorylated in the Head and Rod regions by the PKC kinase PKN1, leading to inhibit polymerization (By similarity). MISCELLANEOUS: NF-L is the most abundant of the three neurofilament proteins and, as the other nonepithelial intermediate filament proteins, it can form homopolymeric 10-nm filaments. SIMILARITY: Belongs to the intermediate filament family. GENE SYNONYMS: Nf68 Nfl. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| skos:exactMatch | |
| skos:closeMatch |