| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Fibroblast growth factor receptor substrate 3
|
| http://www.biopax.org/relea... |
FRS3_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
FGFR substrate 3,
FGFR-signaling adaptor SNT2,
SNT-2,
Suc1-associated neurotrophic factor target 2
|
| http://www.biopax.org/relea... |
FUNCTION: Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. SUBUNIT: Binds NTRK1 (By similarity). Binds FGFR1, NGFR, GRB2, PTPN11 and ERK2. SUBCELLULAR LOCATION: Membrane; Lipid-anchor. PTM: Phosphorylated on tyrosine residues upon stimulation by BFGF or NGFB. SIMILARITY: Contains 1 IRS-type PTB domain. SEQUENCE CAUTION: Sequence=CAI13184.2; Type=Erroneous gene model prediction; COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |