| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-577174,
cpath:CPATH-LOCAL-577175,
cpath:CPATH-LOCAL-577176,
cpath:CPATH-LOCAL-577177,
cpath:CPATH-LOCAL-577178,
cpath:CPATH-LOCAL-577179,
cpath:CPATH-LOCAL-577180,
cpath:CPATH-LOCAL-577181,
cpath:CPATH-LOCAL-577182,
cpath:CPATH-LOCAL-577183,
cpath:CPATH-LOCAL-577184,
cpath:CPATH-LOCAL-577185,
cpath:CPATH-LOCAL-577186,
cpath:CPATH-LOCAL-581162
|
| http://www.biopax.org/relea... |
Asialoglycoprotein receptor 2
|
| http://www.biopax.org/relea... |
ASGR2_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
ASGP-R 2,
ASGPR 2,
C-type lectin domain family 4 member H2,
HL-2,
Hepatic lectin H2
|
| http://www.biopax.org/relea... |
FUNCTION: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. SUBUNIT: The functioning ligand-binding unit of this receptor is thought to be at least a dimer. Interacts with LASS2. SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=P07307-1; Sequence=Displayed; Name=2; IsoId=P07307-2; Sequence=VSP_003060; Name=3; IsoId=P07307-3; Sequence=VSP_003060, VSP_003061; TISSUE SPECIFICITY: Expressed exclusively in hepatic parenchymal cells. MISCELLANEOUS: Calcium is required for ligand binding. SIMILARITY: Contains 1 C-type lectin domain. WEB RESOURCE: Name=Functional Glycomics Gateway - Glycan Binding; Note=Hepatic asialoglycoprotein receptor subunit 2; URL="http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Ctlect_216"; GENE SYNONYMS: CLEC4H2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |