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PredicateObject
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Transcription factor BTF3
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BTF3_HUMAN
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RNA polymerase B transcription factor 3
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FUNCTION: General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription. SUBCELLULAR LOCATION: Nucleus. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; Synonyms=BTF3a; IsoId=P20290-1; Sequence=Displayed; Name=2; Synonyms=BTF3b; IsoId=P20290-2; Sequence=VSP_013587; PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. SIMILARITY: Belongs to the NAC-beta family. SIMILARITY: Contains 1 NAC-A/B (NAC-alpha/beta) domain. GENE SYNONYMS: NACB. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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