Statements in which the resource exists as a subject.
PredicateObject
rdf:type
http://www.biopax.org/relea...
http://www.biopax.org/relea...
Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 2
http://www.biopax.org/relea...
BIRC2_HUMAN, BIRC2_HUMAN, BIRC2_HUMAN
http://www.biopax.org/relea...
http://www.biopax.org/relea...
C-IAP1, C-IAP1, C-IAP1, IAP homolog B, IAP homolog B, IAP homolog B, IAP-2, IAP-2, IAP-2, Inhibitor of apoptosis protein 2, Inhibitor of apoptosis protein 2, Inhibitor of apoptosis protein 2, RING finger protein 48, RING finger protein 48, RING finger protein 48, TNFR2-TRAF-signaling complex protein 2, TNFR2-TRAF-signaling complex protein 2, TNFR2-TRAF-signaling complex protein 2, hIAP-2, hIAP-2, hIAP-2, hIAP2, hIAP2, hIAP2
http://www.biopax.org/relea...
FUNCTION: Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). SUBUNIT: Interacts with DIABLO/SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity. Interacts with CASP9. SUBCELLULAR LOCATION: Cytoplasm (Potential). TISSUE SPECIFICITY: Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes. SIMILARITY: Belongs to the IAP family. SIMILARITY: Contains 3 BIR repeats. SIMILARITY: Contains 1 CARD domain. SIMILARITY: Contains 1 RING-type zinc finger. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/birc2/"; GENE SYNONYMS: API1 IAP2 MIHB RNF48. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License., FUNCTION: Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). SUBUNIT: Interacts with DIABLO/SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity. Interacts with CASP9. SUBCELLULAR LOCATION: Cytoplasm (Potential). TISSUE SPECIFICITY: Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes. SIMILARITY: Belongs to the IAP family. SIMILARITY: Contains 3 BIR repeats. SIMILARITY: Contains 1 CARD domain. SIMILARITY: Contains 1 RING-type zinc finger. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/birc2/"; GENE SYNONYMS: API1 IAP2 MIHB RNF48. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License., FUNCTION: Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). SUBUNIT: Interacts with DIABLO/SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity. Interacts with CASP9. SUBCELLULAR LOCATION: Cytoplasm (Potential). TISSUE SPECIFICITY: Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes. SIMILARITY: Belongs to the IAP family. SIMILARITY: Contains 3 BIR repeats. SIMILARITY: Contains 1 CARD domain. SIMILARITY: Contains 1 RING-type zinc finger. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/birc2/"; GENE SYNONYMS: API1 IAP2 MIHB RNF48. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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