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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Sister chromatid cohesion protein DCC1
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| http://www.biopax.org/relea... |
DCC1_YEAST
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Defective in sister chromatid cohesion protein 1
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| http://www.biopax.org/relea... |
FUNCTION: Component of the RFC-like complex CTF18-RFC which is required for efficient establishment of chromosome cohesion during S-phase and may load or unload POL30/PCNA. During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC. The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit. Dissociation of RFC from the clamp leaves the clamp encircling DNA. SUBUNIT: Component of the CTF18-RFC complex, which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. MISCELLANEOUS: Present with 1660 molecules/cell in log phase SD medium. SIMILARITY: Belongs to the DCC1 family. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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