| Predicate | Object |
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| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Laminin subunit alpha-5
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| http://www.biopax.org/relea... |
LAMA5_HUMAN
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Laminin-10 subunit alpha,
Laminin-11 subunit alpha,
Laminin-15 subunit alpha
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| http://www.biopax.org/relea... |
FUNCTION: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. SUBUNIT: Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-5 is a subunit of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component. TISSUE SPECIFICITY: Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver. DOMAIN: Domain G is globular and is part of the major cell-binding site located in the long arm of the laminin heterotrimer. SIMILARITY: Contains 22 laminin EGF-like domains. SIMILARITY: Contains 5 laminin G-like domains. SIMILARITY: Contains 1 laminin IV type A domain. SIMILARITY: Contains 1 laminin N-terminal domain. SEQUENCE CAUTION: Sequence=CAC22310.1; Type=Erroneous gene model prediction; GENE SYNONYMS: KIAA0533 KIAA1907. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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