| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Cyclin-dependent kinase 6,
Cyclin-dependent kinase 6
|
| http://www.biopax.org/relea... |
CDK6_HUMAN,
CDK6_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
2.7.11.22,
2.7.11.22,
Cell division protein kinase 6,
Cell division protein kinase 6,
Serine/threonine-protein kinase PLSTIRE,
Serine/threonine-protein kinase PLSTIRE
|
| http://www.biopax.org/relea... |
FUNCTION: Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins. CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. INDUCTION: Down-regulated in response to enterovirus 71 (EV71) infection. POLYMORPHISM: Genetic variations in CDK6 may influence stature as a quantitative trait, contributing to the stature quantitative trait locus 11 (STQTL11) [MIM:612223]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits. SIMILARITY: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. SIMILARITY: Contains 1 protein kinase domain. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/cdk6/"; COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
FUNCTION: Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins. CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. INDUCTION: Down-regulated in response to enterovirus 71 (EV71) infection. POLYMORPHISM: Genetic variations in CDK6 may influence stature as a quantitative trait, contributing to the stature quantitative trait locus 11 (STQTL11) [MIM:612223]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits. SIMILARITY: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. SIMILARITY: Contains 1 protein kinase domain. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/cdk6/"; COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
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