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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Probable phospholipid-transporting ATPase NEO1
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| http://www.biopax.org/relea... |
ATC7_YEAST
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| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
3.6.3.1
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| http://www.biopax.org/relea... |
FUNCTION: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of phospholipids (Potential). Leads to neomycin-resistance when overexpressed. Required for traffic between late Golgi and early endosomes. CATALYTIC ACTIVITY: ATP + H(2)O + phospholipid(In) = ADP + phosphate + phospholipid(Out). SUBUNIT: Interacts with MON2. SUBCELLULAR LOCATION: Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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