| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Lymphotoxin-beta
|
| http://www.biopax.org/relea... |
TNFC_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
LT-beta,
TNF-C,
Tumor necrosis factor C,
Tumor necrosis factor ligand superfamily member 3
|
| http://www.biopax.org/relea... |
FUNCTION: Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional. SUBUNIT: Heterotrimer of either two LTB and one LTA subunits or (less prevalent) one LTB and two LTA subunits. SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein (Potential). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q06643-1; Sequence=Displayed; Name=2; IsoId=Q06643-2; Sequence=VSP_006441, VSP_006442; TISSUE SPECIFICITY: Spleen and thymus. SIMILARITY: Belongs to the tumor necrosis factor family. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/ltb/"; WEB RESOURCE: Name=SeattleSNPs; URL="http://pga.gs.washington.edu/data/ltb/"; GENE SYNONYMS: TNFC TNFSF3. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
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