14805

Source:http://linkedlifedata.com/resource/chembl/compound/14805

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Named Graph Language Inference

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	chembl:ChemicalCompound
chemicalCompound:synonym	synonym:14805_Lapatinib_FDA_ALTERNATIVE_NAME, synonym:14805_Lapatinib_INN, synonym:14805_Tykerb_TRADE_NAME
chemicalCompound:standardIn...	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)
chemicalCompound:standardIn...	BCFGMOOMADDAQU-UHFFFAOYSA-N
chemicalCompound:canonicalS...	CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2
chemicalCompound:molecularF...	C29H26ClFN4O4S
chemicalCompound:moleculeId	14805
chemicalCompound:mwFreebase	581.058
chemicalCompound:alogp	6.041
chemicalCompound:hba	7
chemicalCompound:hbd	2
chemicalCompound:psa	114.73
chemicalCompound:rtb	11
chemicalCompound:ro3Pass	N
chemicalCompound:numRo5viol...	2
chemicalCompound:medChemFri...	Y
chemicalCompound:acdLogP	6.302
chemicalCompound:acdLogD	6.262
chemicalCompound:molecularS...	molecularSpecies:NEUTRAL
chemicalCompound:fullMwt	581.058
chemicalCompound:acdMostBpk...	6.341
chemicalCompound:chemblId	CHEMBL554
chemicalCompound:maxPhase	4
chemicalCompound:therapeuti...	1
chemicalCompound:dosedIngre...	No
chemicalCompound:structureT...	structureType:MOL
chemicalCompound:chebi	https://linkedlifedata.com/resource/chebi/id/CHEBI:114805
chemicalCompound:moleculeTy...	moleculeType:Small molecule
chemicalCompound:oral	Yes
chemicalCompound:parenteral	No
chemicalCompound:topical	No
chemicalCompound:blackBoxWa...	No
chemicalCompound:naturalPro...	No
chemicalCompound:proDrug	No
chemicalCompound:prefName	LAPATINIB
chemicalCompound:chebiParen...	https://linkedlifedata.com/resource/chebi/id/CHEBI:49603
chemicalCompound:firstAppro...	2007
chemicalCompound:activity	activity:190221, activity:190222, activity:1650000, activity:1650009, activity:1650018, activity:1650027, activity:1650036, activity:1650045, activity:1650054, activity:1650063, activity:1650072, activity:1650081, activity:1650090, activity:1650099, activity:1650108, activity:1650117, activity:1650126, activity:1650135, activity:1650144, activity:1650153, activity:1650162, activity:1650171, activity:1650180, activity:1650189, activity:1650198, activity:1650207, activity:1650216, activity:1650225, activity:1650234, activity:1650243, activity:1650252, activity:1650261, activity:1650270, activity:1650279, activity:1650288, activity:1650297, activity:1650306, activity:1650315, activity:1650324, activity:1650333, activity:1650342, activity:1650351, activity:1650360, activity:1650369, activity:1650378, activity:1650387, activity:1650396, activity:1650405, activity:1650414, activity:1650423, activity:1650432, activity:1650441, activity:1650450, activity:1650459, activity:1650468, activity:1650477, activity:1650486, activity:1650495, activity:1650504, activity:1650513, activity:1650522