Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:9123
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder." []
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| skos:inScheme | |
| skos:prefLabel |
sertraline
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| skos:altLabel |
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine,
Sertraline
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| skos:notation |
ChemIDplus:5753709 "Beilstein Registry Number",
ChemIDplus:79617-96-2 "CAS Registry Number",
CiteXplore:19502000 "PubMed citation",
CiteXplore:21823671 "PubMed citation",
DrugBank:DB01104 "DrugBank",
HMDB:HMDB05010 "HMDB",
KEGG COMPOUND:79617-96-2 "CAS Registry Number",
KEGG COMPOUND:C07246 "KEGG COMPOUND",
KEGG DRUG:D02360 "KEGG DRUG",
NIST Chemistry WebBook:79617-96-2 "CAS Registry Number",
Patent:US4536518 "Patent",
Reaxys:5753709 "Reaxys Registry Number",
Wikipedia:Sertraline "Wikipedia"
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| skos:broader | |
| skos:relatedSynonym |
sertraline,
sertralinum,
sertralina,
CP 51974,
cis-(+)-sertraline,
(1S,4S)-sertraline,
(+)-sertraline,
(1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine,
C17H17Cl2N,
[H][C@]1(CC[C@H](NC)c2ccccc12)c1ccc(Cl)c(Cl)c1,
InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1,
InChIKey=VGKDLMBJGBXTGI-SJCJKPOMSA-N
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