Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:70746
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amino group of ethyl N-pyridin-2-yl-beta-alaninate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism." []
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| skos:inScheme | |
| skos:prefLabel |
dabigatran etexilate
|
| skos:altLabel |
ethyl N-[(2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alaninate
|
| skos:notation |
ChemIDplus:211915-06-9 "CAS Registry Number",
CiteXplore:21265583 "PubMed citation",
CiteXplore:21429525 "PubMed citation",
CiteXplore:21542663 "PubMed citation",
CiteXplore:21748501 "PubMed citation",
CiteXplore:21859976 "PubMed citation",
CiteXplore:21881389 "PubMed citation",
CiteXplore:22252796 "PubMed citation",
CiteXplore:22276081 "PubMed citation",
CiteXplore:22298812 "PubMed citation",
CiteXplore:22318514 "PubMed citation",
CiteXplore:22348256 "PubMed citation",
CiteXplore:22422743 "PubMed citation",
CiteXplore:22431533 "PubMed citation",
CiteXplore:22488474 "PubMed citation",
CiteXplore:22536678 "PubMed citation",
CiteXplore:22552763 "PubMed citation",
CiteXplore:22563715 "PubMed citation",
CiteXplore:22564134 "PubMed citation",
CiteXplore:22669799 "PubMed citation",
CiteXplore:22782539 "PubMed citation",
CiteXplore:22803489 "PubMed citation",
CiteXplore:22995531 "PubMed citation",
HMDB:HMDB15641 "HMDB",
KEGG DRUG:211915-06-9 "CAS Registry Number",
KEGG DRUG:D07144 "KEGG DRUG",
Patent:US2011275824 "Patent",
Patent:WO2007047608 "Patent",
Patent:WO2011061080 "Patent",
Patent:WO2012027543 "Patent",
Patent:WO2012077136 "Patent",
Reaxys:15496119 "Reaxys Registry Number"
|
| skos:broader | |
| skos:relatedSynonym |
dabigatran etexilate,
C34H41N7O5,
CCCCCCOC(=O)\\N=C(\\N)c1ccc(NCc2nc3cc(ccc3n2C)C(=O)N(CCC(=O)OCC)c2ccccn2)cc1,
InChI=1S/C34H41N7O5/c1-4-6-7-10-21-46-34(44)39-32(35)24-12-15-26(16-13-24)37-23-30-38-27-22-25(14-17-28(27)40(30)3)33(43)41(20-18-31(42)45-5-2)29-11-8-9-19-36-29/h8-9,11-17,19,22,37H,4-7,10,18,20-21,23H2,1-3H3,(H2,35,39,44),
InChIKey=KSGXQBZTULBEEQ-UHFFFAOYSA-N
|