Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:68558
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A triazolopyrimidine that is an adenosine isostere; the cyclopentane ring is similar to ribose and the nitrogen-rich [1,2,3]triazolo[4,5-d]pyrimidine moiety resembles the nucleobase adenine. A platelet aggregation inhibitor which is used for prevention of thromboembolic events in patients with acute coronary syndrome." []
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| skos:inScheme | |
| skos:prefLabel |
ticagrelor
|
| skos:altLabel |
(1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
|
| skos:notation |
ChemIDplus:274693-27-5 "CAS Registry Number",
CiteXplore:22991347 "PubMed citation",
HMDB:HMDB15702 "HMDB",
KEGG DRUG:D09017 "KEGG DRUG",
Patent:WO2012085665 "Patent",
Reaxys:15468079 "Reaxys Registry Number"
|
| skos:broader | |
| skos:relatedSynonym |
ticagrelor,
AZD 6140,
AZD-6140,
Brilinta,
AZD6140,
(1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol,
C23H28F2N6O4S,
CCCSc1nc(N[C@@H]2C[C@H]2c2ccc(F)c(F)c2)c2nnn([C@@H]3C[C@H](OCCO)[C@@H](O)[C@H]3O)c2n1,
InChI=1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1,
InChIKey=OEKWJQXRCDYSHL-FNOIDJSQSA-N
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