Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:68540
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A carboxamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis." []
|
| skos:inScheme | |
| skos:prefLabel |
teriflunomide
|
| skos:altLabel |
(2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
|
| skos:notation |
ChemIDplus:163451-81-8 "CAS Registry Number",
CiteXplore:20880295 "PubMed citation",
CiteXplore:21349677 "PubMed citation",
CiteXplore:21367665 "PubMed citation",
CiteXplore:21425264 "PubMed citation",
CiteXplore:21625416 "PubMed citation",
CiteXplore:21991951 "PubMed citation",
CiteXplore:22012334 "PubMed citation",
CiteXplore:22052286 "PubMed citation",
CiteXplore:22052362 "PubMed citation",
CiteXplore:22148963 "PubMed citation",
CiteXplore:22229697 "PubMed citation",
CiteXplore:22278631 "PubMed citation",
CiteXplore:22307384 "PubMed citation",
CiteXplore:22398660 "PubMed citation",
CiteXplore:22426573 "PubMed citation",
CiteXplore:22612746 "PubMed citation",
CiteXplore:22622860 "PubMed citation",
CiteXplore:22673950 "PubMed citation",
CiteXplore:22723573 "PubMed citation",
CiteXplore:22766059 "PubMed citation",
CiteXplore:22784880 "PubMed citation",
CiteXplore:22796174 "PubMed citation",
CiteXplore:22960763 "PubMed citation",
CiteXplore:22965070 "PubMed citation",
KEGG DRUG:163451-81-8 "CAS Registry Number",
KEGG DRUG:D10172 "KEGG DRUG",
PDBeChem:A26 "PDBeChem",
Reaxys:6655982 "Reaxys Registry Number",
Wikipedia:Teriflunomide "Wikipedia"
|
| skos:broader | |
| skos:relatedSynonym |
teriflunomide,
Aubagio,
HMR 1726,
HMR1726,
A 77-1726,
A 771726,
(Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide,
C12H9F3N2O2,
C\\C(O)=C(/C#N)C(=O)Nc1ccc(cc1)C(F)(F)F,
InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-,
InChIKey=UTNUDOFZCWSZMS-YFHOEESVSA-N
|