Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:68534
Predicate | Object |
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rdf:type | |
skos:definition |
"A benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with methylamine. Used for the treatment of of metastatic castration-resistant prostate cancer." []
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skos:inScheme | |
skos:prefLabel |
enzalutamide
|
skos:altLabel |
4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluoro-N-methylbenzamide
|
skos:notation |
ChemIDplus:915087-33-1 "CAS Registry Number",
CiteXplore:21986558 "PubMed citation",
CiteXplore:22101903 "PubMed citation",
CiteXplore:22113551 "PubMed citation",
CiteXplore:22162475 "PubMed citation",
CiteXplore:22229405 "PubMed citation",
CiteXplore:22258371 "PubMed citation",
CiteXplore:22258374 "PubMed citation",
CiteXplore:22266222 "PubMed citation",
CiteXplore:22310230 "PubMed citation",
CiteXplore:22373838 "PubMed citation",
CiteXplore:22393799 "PubMed citation",
CiteXplore:22411952 "PubMed citation",
CiteXplore:22429837 "PubMed citation",
CiteXplore:22472508 "PubMed citation",
CiteXplore:22516457 "PubMed citation",
CiteXplore:22710436 "PubMed citation",
CiteXplore:22815001 "PubMed citation",
CiteXplore:22845410 "PubMed citation",
CiteXplore:22852027 "PubMed citation",
CiteXplore:22894553 "PubMed citation",
CiteXplore:22956944 "PubMed citation",
CiteXplore:22985411 "PubMed citation",
CiteXplore:22987974 "PubMed citation",
Patent:US2007254933 "Patent",
Patent:WO2006124118 "Patent",
Patent:WO2011106570 "Patent",
Reaxys:11718700 "Reaxys Registry Number",
Wikipedia:Enzalutamide "Wikipedia"
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skos:broader | |
skos:relatedSynonym |
MDV-3100,
MDV3100,
XTANDI,
MDV 3100,
C21H16F4N4O2S,
CNC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C1(C)C)c1ccc(C#N)c(c1)C(F)(F)F,
InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30),
InChIKey=WXCXUHSOUPDCQV-UHFFFAOYSA-N
|