Statements in which the resource exists as a subject.
PredicateObject
rdf:type
skos:definition
"A benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with methylamine. Used for the treatment of of metastatic castration-resistant prostate cancer." []
skos:inScheme
skos:prefLabel
enzalutamide
skos:altLabel
4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluoro-N-methylbenzamide
skos:notation
ChemIDplus:915087-33-1 "CAS Registry Number", CiteXplore:21986558 "PubMed citation", CiteXplore:22101903 "PubMed citation", CiteXplore:22113551 "PubMed citation", CiteXplore:22162475 "PubMed citation", CiteXplore:22229405 "PubMed citation", CiteXplore:22258371 "PubMed citation", CiteXplore:22258374 "PubMed citation", CiteXplore:22266222 "PubMed citation", CiteXplore:22310230 "PubMed citation", CiteXplore:22373838 "PubMed citation", CiteXplore:22393799 "PubMed citation", CiteXplore:22411952 "PubMed citation", CiteXplore:22429837 "PubMed citation", CiteXplore:22472508 "PubMed citation", CiteXplore:22516457 "PubMed citation", CiteXplore:22710436 "PubMed citation", CiteXplore:22815001 "PubMed citation", CiteXplore:22845410 "PubMed citation", CiteXplore:22852027 "PubMed citation", CiteXplore:22894553 "PubMed citation", CiteXplore:22956944 "PubMed citation", CiteXplore:22985411 "PubMed citation", CiteXplore:22987974 "PubMed citation", Patent:US2007254933 "Patent", Patent:WO2006124118 "Patent", Patent:WO2011106570 "Patent", Reaxys:11718700 "Reaxys Registry Number", Wikipedia:Enzalutamide "Wikipedia"
skos:broader
skos:relatedSynonym
MDV-3100, MDV3100, XTANDI, MDV 3100, C21H16F4N4O2S, CNC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C1(C)C)c1ccc(C#N)c(c1)C(F)(F)F, InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30), InChIKey=WXCXUHSOUPDCQV-UHFFFAOYSA-N