Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:63450
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]benzene-1,3-diamine. It is a highly selective oral tyrosine kinase inhibitor." []
|
| skos:inScheme | |
| skos:prefLabel |
masitinib
|
| skos:altLabel |
4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)benzamide
|
| skos:notation |
ChemIDplus:790299-79-5 "CAS Registry Number",
CiteXplore:19549290 "PubMed citation",
CiteXplore:19789626 "PubMed citation",
CiteXplore:20033487 "PubMed citation",
CiteXplore:20211560 "PubMed citation",
CiteXplore:21034327 "PubMed citation",
CiteXplore:21333567 "PubMed citation",
CiteXplore:21504563 "PubMed citation",
CiteXplore:21668810 "PubMed citation",
Reaxys:12083382 "Reaxys Registry Number"
|
| skos:broader | |
| skos:relatedSynonym |
masitinib,
AB1010,
AB 1010,
AB-1010,
C28H30N6OS,
CN1CCN(CC1)Cc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nc(cs2)-c2cccnc2)c1,
InChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15,18H2,1-2H3,(H,30,35)(H,31,32),
InChIKey=WJEOLQLKVOPQFV-UHFFFAOYSA-N
|